For those individuals considering the submission of a symposium proposal, here is a list of some recent symposia of greatest interest to Drug Metabolism Division members:

ASPET/ASBMB: Boston MA, June 2000

Molecular Regulation of Genes Encoding Xenobiotic Metabolizing Enzymes:
Mechanisms Involving Endogenous Factors Chair: Ronald N. Hines

Molecular Regulation of Genes Encoding Xenobiotic Metabolizing Enzymes:
Mechanisms Involving Exogenous Factors Chair: Russell A. Prough

The Structure and Function of Cytochrome P450 Chair: Lucy Waskell

The Pharmacogenetics/Genomics of Cytochrome P450 Chair: Frank J. Gonzalez

Pharmacogenetics of the Arylamine N-Acetyltransferases: A Symposium in Honor
of Wendell W. Weber Chair: David W. Hein

Drug Metabolism in Animal Models of Human Disease Chair: David D. Christ

Glucuronidation and the UDP-Glycosyltransferases (UGTs) in Drug Therapy and
Disease Chairs: Peter G. Wells and Joseph K. Ritter

Physiological Significance and Cross-talk of bHLH-PAS Proteins
Chair: Linda S. Birnbaum,


Experimental Biology 2001: Orlando FL, April 2001

Mechanisms of nuclear receptor-mediated cytochrome P450 induction
Chair: T.A. Kocarek

Cytochrome P450 as a source and a target of nitric oxide Chair: E.T. Morgan.

Pharmacokinetic and molecular understanding for the development of
thiazolidinediones: SAR Chair: H.M. Rhee.

Current progress of esterases: from molecules to functions Chair: T. Satoh.


Experimental Biology 2002: New Orleans LA, April 2002

Regulation and function of human extrahepatic cytochrome P450 Chair: Xinxin Ding

Regulation and pharmacogenetics of the flavin-containing monooxygenases
Chair: Ronald N. Hines

Advances in understanding transport of drugs and toxicants
Chairs: Gary O. Rankin and Mary Vore

Mechanisms of higher sensitivity of drugs and environmental toxicants in
diabetes Chairs: Harihara M. Mehendale and John B. Watkins,

The role of genotyping in prescribing and drug development
Chair: Alastair J. Wood

Post transcriptional regulation of drug metabolizing enzymes
Chair: Dennis R. Koop

graduate and postdoctoral training in drug metabolism: view points from
academia, industry and government Chairs: Dennis R. Koop and Jeffrey Stevens

TOXICOLOGY DIVISION ROUNDTABLE: Genetics and susceptibility to toxic
chemicals: Do you (or should you) know your genetic profile? Chair: Larry H. Lash


Experimental Biology 2003: San Diego, CA, April 2003

Use of genomic data on drug-metabolizing enzymes and transporters to assess risk Chair: Richard Okita

Regulation and physiological functions of extrahepatic cytosolic sulfotransferases Chair: Charles N. Falany

Structural domains and motifs: Functional implications for drug-sensing transcription factors. Chair: Masahiko Negishi

Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals. Chair: David S. Riddick


Experimental Biology 2004: Washington, D.C., April 2004

Mechanisms of adverse drug reactions. Chair: Ronald N. Hines
Knockout mouse models for studying in vivo function of cytochrome P450 and other drug metabolizing enzymes. Chair: Xinxin Ding
Early ADME support and the drug discovery process. Chair: Adedayo Adedoyin
Cancer chemotherapy and drug metabolism. Chair: David S. Riddick


Experimental Biology 2005:  San Diego, CA, April 2-6, 2005.

Developmental Expression of Drug Metabolizing Enzymes and Impact on Pediatric Clinical Pharmacology

(co-sponsored with the Systems and Integrative Pharmacology Division) Chair: Jeffrey C. Stevens.
Glucuronosyltransferases: Their Role in Drug Interactions and Toxicity
(co-sponsored with the Pharmacology Education Division)  Chairs: Rory P. Remmel and Timothy S. Tracy.
Modulation of toxicity via glucuronidation. Philip C. Smith, Univ. of North Carolina at Chapel Hill
Role of Xenobiotic Metabolizing Enzymes in the Homeostatic Control of Endogenous Substrates
Chair: Robert L. Haining.

Pharmacogenetics and Pharmacogenomics Knowledge Base (PharmGKB) and the Scientific Community: An Interactive Workshop

Chairs: Timothy S. Tracy and David S. Riddick.

Protein Modification During Oxidative Injury (Co-sponsored with Toxicology Division) Chairs: Daniel C. Lieber and Serrine S. Lau.
Division for Drug Metabolism Platform Session: Biotransformation and Drug Transport. James Gillette Best Paper Awards and selected contributed paper presentations. 

Chairs: Timothy S. Tracy and David S. Riddick.

Experimental Biology 2006:  San Francisco, CA, April 1-5, 2006

 What Regulates the Regulators? Factors that Alter Expression of the Nuclear Receptors Which Regulate Drug-metabolizing Enzymes. Chairs: Allan B. Okey and David S. Riddick
Metabolomic/Metabonomic Probes of Drug Metabolism Consequences. Chair: Larry S. Kaminsky
Function, Regulation, and Genetic Polymorphisms of the Cytochrome P450 Reductase.
Chair: Xinxin Ding
Metabolic Considerations in the Action of Herbal Medicines. Chair: Thomas K.H. Chang

Experimental Biology 2007:  Washington, D.C., April 28-May 5, 2006

Pharmacogenomics: Frontiers to the Future. Chairs: Rochelle M. Long and Richard M. Weinshilboum

Recent Advances in our Understanding of the Flavin-containing Monooxygenases: Role in Disease and Adverse Drug Reactions: In Memory of Daniel Ziegler.

Chairs: Ronald N. Hines and David E. Williams

Regulation of Drug Metabolizing Enzymes and Transporters in Inflammatory Disease States: A Symposium in Honor of the Career of Dr. Kenneth W. Renton.

Chair: Edward T. Morgan

Genetic Variations in Regulatory Factors Affecting Drug Metabolism/Disposition.

Chair: Erin Schuetz


Experimental Biology 2008:  San Diego, CA, April 5-9, 2008

P450s: Structure, Function, In Silico Predictions. Chairs: James R. Halpert and Eric F. Johnson

Drug Metabolism, Bioactivation & Chemical-induced Toxicities:  Lessons Learned & Contemporary Issues.

Chairs: Terry J. Monks and Kenneth E. Thummel


Experimental Biology 2009: New Orleans, LA, April 18-22, 2009

Targeting Drug Metabolizing Enzymes for Effective Chemopreventive Approaches. Chairs: Hollie Swanson and Emily E. Scott

Regulation of Xenobiotic Metabolizing Enzymes in Humans: Implications for the Propagation of Health and Disease. Chairs:  Charles N. Falany and Melissa Runge-Morris